Pharmacological Significance of Synthetic Heterocycles Scaffold: A Review

Abstract: Heterocyclic chemistry offers an example for the lack of distinct demarcations; in fact, it pervades the plurality of the other chemical disciplines. Heterocycles are inextricably woven into the life processes. The vital interest of the pharmaceutical and agrochemical industries in heterocycles is often connected with their natural occurrence. Synthetic chemistry provides cornucopia of heterocyclic systems. More than 90% of new drugs contain heterocycles and the interface between chemistry and biology, at which so much new scientific insight, discovery and application is taking place is crossed by heterocyclic compounds. This review article covers the most active heterocycles that have shown considerable biological actions such as antibiotic, antifungal, antiinflammatory, antiviral, anticancer, anticonvulsant, anthelmintic,antihistamine, antidepressant activities.